| Aces for Autism | 3914 | Independent Charity | HOPE, JOY, SUCCESS Aces for Autism walks alongside individuals and families impacted by autism providing a variety of services to meet the needs of each individual. |
| Alex’s Lemonade Stand Fndn. | 1973 | America's Best Charities | A four-year-old cancer patient's frontyard lemonade stand evolved to a nationwide movement to find a cure for pediatric cancer. Every person can make a difference. |
| Alight | 1389 | Global Impact | Building a meaningful life for and with the displaced. Not simply addressing basic needs, but building a life filled with joy, dignity, connection and purpose. |
| Alliance of AIDS Services, Carolina | 1802 | Independent Charity | Alliance improves the health of communities impacted by HIV/AIDS through compassionate and non-judgmental prevention, support services, and connection to care. |
| Alpha-1 Fndn. | 2454 | CHC: Creating Healthier Communities | The Alpha-1 Foundation is committed to finding a cure for Alpha-1 Antitrypsin Deficiency and to improving the lives of people affected by Alpha-1 worldwide. |
| ALS United NC | 1031 | Independent Charity | We provide care services, access to research and advocate for policies that directly impact the ALS Community in NC. |
| Alzheimer’s Fndn. of America | 2911 | America's Best Charities | Providing programs & services, including caregiver counseling & support from licensed social workers, educational materials, professional training & funding for research. |
| Alzheimer’s Research & Prevention Fndn. | 2046 | America's Best Charities | Help fight Alzheimer's disease and find a cure through research and prevention! |
| Alzheimers Disease & Related Disorders Assoc., Eastern NC | 1056 | CHC: Creating Healthier Communities | The leading voluntary health organization in Alzheimer’s care and support and the largest private, nonprofit funder of Alzheimer’s research. |
| Alzheimers Disease & Related Disorders Assoc., Western NC | 1041 | CHC: Creating Healthier Communities | The leading voluntary health organization in Alzheimer’s care and support and the largest private, nonprofit funder of Alzheimer’s research. |
| Alzheimer’s Research Fndn., Fisher Center | 1998 | America's Best Charities | Unique research into cause, care and cure of Alzheimer's by Nobel Prize winner. Donate to change lives. Bring a cure to 5.4 million Americans. |
| American Assoc. for Cancer Research | 1974 | America's Best Charities | We fund groundbreaking scientific cancer research that saves lives. By contributing, you can help speed up the pace of scientific discovery, and fight cancer. |
| American Assoc. of Kidney Patients | 2047 | America's Best Charities | AAKP fights for early detection; increased kidney transplantation/pre-emptive transplantation; full patient choice/either in-center or home dialysis. |
| American Cancer Society | 1504 | CHC: Creating Healthier Communities | Improving lives of people with cancer and their families through advocacy, research, and patient support, working to end cancer as we know it, for everyone. |
| American Cancer Society, NC Chapter | 7051 | Independent Charity | Through advocacy, research, & patient support, the American Cancer Society is the leading cancer-fighting organization with a vision to end cancer as we know it, for everyone. |
| American Fndn. for Children with AIDS | 2920 | America's Best Charities | We provide anti-retroviral and other medication, livelihood programs, and supplies to help children with AIDS achieve their full potential. |
| American Kidney Fund | 1005 | CHC: Creating Healthier Communities | We fight kidney disease by addressing education, advocacy, financial assistance, prevention, research; spending 97 cents of every donated dollar on programs. |
| American Liver Fndn. | 1091 | CHC: Creating Healthier Communities | The nation's leading non-profit that facilitates, advocates and promotes education, support and research for prevention, treatment and cure of liver disease. |
| American Near East Refugee Aid | 1304 | Global Impact | Provides humanitarian assistance and sustainable development to advance the well-being of refugees and other vulnerable communities in the Middle East. |
| American Red Cross – NC | 3835 | Independent Charity | The American Red Cross prevents and alleviates human suffering in the face of emergencies by mobilizing the power of volunteers and the generosity of donors. |
| Americares Fndn. | 1348 | Global Impact | To save lives and improve health for people affected by poverty or disaster so they can reach their full potential. |
| Amref Health Africa | 1302 | Global Impact | Amref's mission is to empower the people of Africa, through better health, to escape poverty and improve the quality of their lives. |
| Anxiety & Depression Assoc. of America | 5052 | America's Best Charities | We champion research for a cure and offer educational resources to millions suffering from anxiety disorders, depression, OCD, and PTSD. |
| Arthritis Fndn. | 1034 | CHC: Creating Healthier Communities | The Arthritis Foundation pursues a cure for America's #1 cause of disability while championing the fight to conquer arthritis with science, resources, advocacy, and community. |
| Autism Research Org. | 2912 | America's Best Charities | Parents of children with autism never stop seeking answers. We're here to provide those answers by funding research that provides practical information on lifelong care. |