| Alley Cat Rescue | 5077 | America's Best Charities - Member | Stray, abandoned and feral cats are neglected. Healthy cats in shelters are killed. Your contribution helps us end feline overpopulation and suffering. |
| Animal League America | 5091 | America's Best Charities - Member | Support the largest no-kill animal rescue and adoption organization in the world. We save the lives of pets through rescue, adoption, spay/neuter, education initiatives. |
| Animal Legal Defense Fund | 1927 | America's Best Charities - Member | Animals need love - and lawyers! Unimaginable acts of cruelty must end. In courtrooms across America, ALDF is winning the case against cruelty! |
| Animal Protection Society, Durham | 4060 | Independent Agency | We build bonds between people and animals while saving lives through education, community outreach and care for animals in need, managing the county animal shelter. |
| AnimalKind | 1529 | Independent Agency | Our mission is to end the unnecessary euthanasia of adoptable cats and dogs in North Carolina Shelters. |
| ASPCA – Prevention of Cruelty to Animals | 1987 | America's Best Charities - Member | Staged dog fights to the death. Puppy factories with overcrowded and unsanitary breeding pens. Kittens tortured for amusement. Help stop these acts of animal cruelty. |
| Assistant Dog Institute | 5094 | America's Best Charities - Member | Our Dogs Helping Veterans program helps heal returning service members by providing loving dog helpmates at no cost to those with physical and psychological disabilities. |
| Best Friends Animal Society | 1692 | America's Charities - Member | For 35+ years, we've run the nation’s largest no-kill sanctuary for companion animals and built effective programs reducing the number of animals entering shelters. |
| Big Cat Rescue Corp | 5020 | America's Best Charities - Member | Tigers confined to circus wagons. Lions bred for photos then to be shot in cages. Lynx farmed for their fur. Help us save big cats. |
| Blind Cat Rescue & Sanctuary | 3859 | Independent Agency | Blind Cat Rescue & Sanctuary provides a safe, loving permanent home and hospice care for blind, FIV- and feline leukemia-positive cats deemed unadoptable. |
| Blue Ridge Parkway Fndn. | 1121 | EarthShare NC - Member | The Blue Ridge Parkway Foundation is the fundraising partner for the Blue Ridge Parkway, providing critical support for initiatives along the 469-mile route. |
| Born Free USA Animal Protection | 1145 | EarthShare NC - Member | Works to end the suffering of wild animals in captivity, rescue individual animals in need, protect wildlife, including endangered species, and encourage compassionate conservation globally. |
| Carolina Tiger Rescue | 1104 | EarthShare NC - Member | Provides rescue and life-long sanctuary to wild cats; conservation education through tours and field trips; community engagement through volunteer opportunities, internships, and company work groups. |
| Chatham Animal Rescue and Education | 3604 | Independent Agency | CARE promotes responsible pet ownership through education and targeted spay-neuter programs, provides foster care for homeless cats and dogs until placed in permanent homes. |
| Corolla Wild Horse Fund | 4169 | Independent Agency | We are committed to protect, conserve, and responsibly manage the wild Banker horses roaming on the northernmost Outer Banks and those rescued from the herd. |
| Days End Farm Horse Rescue | 5055 | America's Best Charities - Member | Starvation, parasite infestation, deformed hoofs. Caring for abused and neglected horses. Dedicated to ensuring quality care and treatment of horses through intervention, education and outreach. |
| Dogs Deserve Better | 5058 | America's Best Charities - Member | Chained by the neck, penned without food or water, receiving abuse, and forced to fight for their lives. Help rescue and rehabilitate these innocent dogs. |
| Dogs Last Chance | 2933 | America's Best Charities - Member | Puppy mills, vivisection/dissection, fur, illegal animal-fighting; Help us end animal abuse! Doing ground breaking undercover investigations to expose animal abusers and promoting cruelty-free lifestyles. |
| Dogs On Death Row | 2018 | America's Best Charities - Member | We rescue dogs facing imminent execution if they do not get interim financial sponsors or foster parents or receive medical treatment required to become adoptable. |
| EarthShare NC | 1100 | EarthShare NC - Fed | Supports 70 conservation organizations working for the environment. We are protecting the health of our communities and their future by connecting people with the organizations making direct impacts in their community |
| Elephant Sanctuary | 2019 | America's Best Charities - Member | The nation's largest natural habitat refuge for endangered elephants retired from circuses and zoos. Improving elephant lives through sanctuary, education, research and overseas assistance. |
| Elephants, Saving Elephants & Habitat Worldwide | 5059 | America's Best Charities - Member | Elephants killed for their ivory. Habitat becomes roads, farms and villages. When elephants and humans cross paths, deaths occur. Help protect elephants, habitat and people. |
| Equine Land Conservation Resource | 2993 | America's Best Charities - Member | No Land, No Horse. We lose 6,000 acres of open land every day. Help Equine Land Conservation Resource save the lands our horses need. |
| Farm Animal Rescue, Adoption, & Sanctuary | 5060 | America's Best Charities - Member | Sanctuary and advocacy for farm animals. Last four years, 16,000 animal lives saved and adopted at our 3 facilities. Mission: Compassion for all life. |
| Farmers & Hunters Feeding the Hungry | 2931 | America's Best Charities - Member | Please help provide nutritious meat to hungry children and families nationwide! We pay the butchering fees for deer and livestock donated by farmers and hunters. |