| African Wildlife Fndn. | 1167 | EarthShare North Carolina - Member Agency | Protects imperiled species-- lions, mountain gorillas, rhinos, elephants,-- through habitat conservation, wildlife protection, leadership training, and wildlife-friendly community-beneficial business development for more than 50 years. |
| Alley Cat Allies | 2919 | America's Best Charities - Member Agency | Every 15 seconds a healthy cat is killed in a shelter. Our programs help shelters save more cats and kittens, but we need your help. |
| Alley Cat Rescue | 5077 | America's Best Charities - Member Agency | Stray, abandoned and feral cats are neglected. Healthy cats in shelters are killed. Your contribution helps us end feline overpopulation and suffering. |
| America’s Best Charities | 1900 | | Feeding the hungry. Sheltering the homeless. Protecting the children. And healing the sick. America's finest independent charities. Working with you to share- the American way. |
| America’s Charities | 1600 | America's Charities | Working to build strong communities. Addressing needs of children, families, communities by helping employers and employees support our member charities' programs. |
| American Kennel Club Canine Health Fndn. | 2922 | America's Best Charities - Member Agency | Help dogs live longer, healthier lives by fighting canine diseases like cancer, epilepsy, eye and heart disease. Our work furthers human treatments and cures, too. |
| Animal Legal Defense Fund | 1927 | America's Best Charities - Member Agency | Animals need love - and lawyers! Unimaginable acts of cruelty must end. In courtrooms across America, ALDF is winning the case against cruelty! |
| Animal Place | 5060 | America's Best Charities - Member Agency | Sanctuary and advocacy for farm animals. Last four years, 16,000 animal lives saved and adopted at our 3 facilities. Mission: Compassion for all life. |
| Animal Protection Society, Durham Co. | 4060 | Independent Charity | We build bonds between people and animals while saving lives through education, community outreach and care for animals in need, managing the county animal shelter. |
| Animal Protection Society, Orange Co. | 3729 | Independent Charity | Paws4ever is a guaranteed adoption animal shelter and sanctuary dedicated to improving the lives of cats and dogs through adoption, training, and education. |
| AnimalKind | 1529 | Independent Charity | To provide low-income families with affordable spay/neuter services through THE $20 FIX Program & a statewide referral service via the SpayNC Helpline. |
| ASPCA – American Society Prevention Cruelty Animals | 1987 | America's Best Charities - Member Agency | Staged dog fights to the death. Puppy factories with overcrowded and unsanitary breeding pens. Kittens tortured for amusement. Help stop these acts of animal cruelty. |
| Assistant Dog Inst., Bergin Univ. | 5094 | America's Best Charities - Member Agency | Our Dogs Helping Veterans program helps heal returning service members by providing loving dog helpmates at no cost to those with physical and psychological disabilities. |
| Best Friends Animal Society | 1692 | America's Charities - Member Agency | For 35+ years, we've run the nation’s largest no-kill sanctuary for companion animals and built effective programs reducing the number of animals entering shelters. |
| Big Cat Rescue Corp | 5020 | America's Best Charities - Member Agency | Tigers confined to circus wagons. Lions bred for photos then to be shot in cages. Lynx farmed for their fur. Help us save big cats. |
| Blind Cat Rescue & Sanctuary | 3859 | Independent Charity | Blind Cat Rescue & Sanctuary is a permanent, safe, and loving home to blind, FIV+ and feline leukemia-positive cats deemed unadoptable and euthanized in shelters. |
| Born Free USA, United with Animal Protection Inst. | 1145 | EarthShare North Carolina - Member Agency | Works to end the suffering of wild animals in captivity, rescue individual animals in need, protect wildlife, including endangered species, and encourage compassionate conservation globally. |
| Canine Assistants | 1989 | America's Best Charities - Member Agency | Teaching great dogs for special people. Invest in freedom by providing service dogs to children and adults with disabilities. Thank you! |
| Canines for Service | 3602 | Independent Charity | CFS provides service dogs at no cost to Veterans from all conflicts with service-connected PTSD, traumatic brain injuries, military sexual trauma, or mobility challenges. |
| CARE – Chatham Animal Rescue Eduction | 577031 | Independent Charity | Promote responsible pet ownership by educating the community, providing targeted spay/neuter programs, and fostering homeless dogs and cats. |
| Carolina Animal Rescue & Adoption | 4103 | Independent Charity | Promote responsible pet ownership through humane education, and to provide shelter and care to domestic companion animals until a forever home can be found |
| Carolina Raptor Center | 1105 | EarthShare North Carolina - Member Agency | Provides environmental education, raptor rehabilitation and raptor medical training worldwide. Visitors to the center enjoy one of the country's largest displays of raptors. |
| Carolina Tiger Rescue, Carnivore Preservation | 1104 | EarthShare North Carolina - Member Agency | Provides rescue and sanctuary for wild cats; conservation education through tours, community outreach and summer camp; and opportunities for volunteering, internships, and community service. |
| Corolla Wild Horse Fund | 4169 | Independent Charity | We are committed to protect, conserve, and responsibly manage the wild Banker horses roaming on the northernmost Outer Banks and those rescued from the herd. |
| Days End Farm Horse Rescue | 5055 | America's Best Charities - Member Agency | Starvation, parasite infestation, deformed hoofs. Caring for abused and neglected horses. Dedicated to ensuring quality care and treatment of horses through intervention, education and outreach. |