| Alley Cat Allies | 2919 | America's Best Charities | Alley Cat Allies is the global engine of change for cats. We work to protect and improve the lives of all cats. |
| Alley Cat Rescue | 5077 | America's Best Charities | Stray, abandoned and feral cats are neglected. Healthy cats in shelters are killed. Your contribution helps us end feline overpopulation and suffering. |
| Animal Legal Defense Fund | 1927 | America's Best Charities | Animals need love - and lawyers! Unimaginable acts of cruelty must end. In courtrooms across America, ALDF is winning the case against cruelty! |
| Animal Place (Farm Animal Rescue) | 5060 | America's Best Charities | Sanctuary and advocacy for farm animals. Last four years, 16,000 animal lives saved and adopted at our 3 facilities. Mission: Compassion for all life. |
| Animal Protection Society, Durham | 4060 | Independent Charity | We strengthen bonds between people and animals through community engagement and compassionate care for animals in need. |
| Animal Protection Society, Orange Co. (Paws4ever) | 3729 | Independent Charity | Paws4ever is a guaranteed adoption animal shelter and sanctuary dedicated to improving the lives of cats and dogs through adoption, training, and education. |
| AnimalKind, Inc | 1529 | Independent Charity | Our mission is to end the unnecessary euthanasia of adoptable cats and dogs in NC shelters. |
| Asheville Humane Society | 3759 | Independent Charity | AHS rescues, reunites, rehabilitates, and rehomes thousands of homeless animals each year and provides community solutions to keep pets healthy and in their homes. |
| ASPCA – American Society for the Prevention of Cruelty to Animals | 1987 | America's Best Charities | Staged dog fights to the death. Puppy factories with overcrowded and unsanitary breeding pens. Kittens tortured for amusement. Help stop these acts of animal cruelty. |
| Big Cat Rescue Corp | 5020 | America's Best Charities | Helping save wild animals. Tigers confined to circus wagons. Lions bred for photos then to be shot in cages. Lynx farmed for their fur. Help us save big cats. |
| Blind Cat Rescue & Sanctuary | 3859 | Independent Charity | We are a safe, loving and healthy permanent home for cats deemed unadoptable and therefore immediately euthanized by most shelters and animal control facilities. |
| Blue Ridge Parkway Fndn. | 1121 | EarthShare North Carolina | The Blue Ridge Parkway Foundation is the fundraising partner for the Blue Ridge Parkway, providing critical support for initiatives along the 469-mile route. |
| Brother Wolf Animal Rescue | 7005 | America's Best Charities | We envision a community where all companion animals are valued, cared for and thriving, and where lives are enriched by the special bond between people and animals. |
| Carolina Animal Rescue & Adoption | 4103 | Independent Charity | We are a shelter that rescues abandoned, injured and abused dogs and cats from harmful situations such as kill shelters, hoarding situations, cat colonies, dog packs, and owner surrenders. |
| Carolina Raptor Center | 1105 | EarthShare North Carolina | Provides environmental education, raptor rehabilitation and raptor medical training worldwide. Visitors to the center enjoy one of the country's largest displays of raptors. |
| Carolina Tiger Rescue | 1104 | EarthShare North Carolina | Provides rescue and life-long sanctuary to wild cats; conservation education through tours and field trips; community engagement through volunteer opportunities, internships, and company work groups. |
| Carolina Waterfowl Rescue | 7009 | Independent Charity | Our unique organization is a 501c3 wildlife and domestic animal rescue, rehabilitation facility and sanctuary serving North Carolina for birds, reptiles, farm and exotic animals. |
| Chatham Animal Rescue & Education | 3604 | Independent Charity | Chatham Animal Rescue & Education promotes the health and safety of all dogs and cats in Chatham County by fostering and promoting population management. |
| Days End Farm Horse Rescue | 5055 | America's Best Charities | Starvation, parasite infestation, deformed hoofs. Caring for abused and neglected horses. Dedicated to ensuring quality care and treatment of horses through intervention, education and outreach. |
| Dogs Last Chance | 2933 | America's Best Charities | Puppy mills, vivisection/dissection, fur, illegal animal-fighting; Help us end animal abuse! Doing ground breaking undercover investigations to expose animal abusers and promoting cruelty-free lifestyles. |
| Dogs On Death Row | 2018 | America's Best Charities | We rescue dogs facing imminent execution if they do not get interim financial sponsors or foster parents or receive medical treatment required to become adoptable. |
| Dorothea Dix Park Conservancy | 4196 | Independent Charity | The Conservancy supports the City of Raleigh in its efforts, serve as its philanthropic partner, and help ensure the creation and long-term success of Dorothea Dix Park. |
| Elephant Sanctuary in Tennessee | 2019 | America's Best Charities | The nation's largest natural habitat refuge for endangered elephants retired from circuses and zoos. Improving elephant lives through sanctuary, education, research and overseas assistance. |
| Elephants, Saving Elephants and Habitat Worldwide | 5059 | America's Best Charities | Elephants killed for their ivory. Habitat becomes roads, farms and villages. When elephants and humans cross paths, deaths occur. Help protect elephants, habitat and people. |
| Equine Land Conservation Resource | 2993 | America's Best Charities | No Land, No Horse. We lose 6,000 acres of open land every day. Help Equine Land Conservation Resource save the lands our horses need. |